Product details

Clone

2C4

Gene ID

1906

Applications

IF(IHC-P)

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Target Protein/Peptide

Endothelin-1

Modification

Not modified

Conjugated with

ALEXA FLUOR 594

Conjugated

Alexa conjugate 1

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Host organism

Mouse (Mus musculus)

Clonality

Monoclonal Antibodies

Purification method

Purified by Protein G.

Type

Conjugated Primary Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Properties

For facs or microscopy Alexa 1 conjugate.

Cross Reactive Species details

No significant cross reactivity is observed

Specificity

Highly specific antibody against Endothelin-1

Cross Reactive species

Human (Homo sapiens), Rat (Rattus norvegicus)

Synonyms

EDN 1; EDN1; EDN1 protein; Endothelin1; ET 1; ET1;

Alternative name 2

Endothelin-1(2C4) Monoclonal anti-, ALEXA FLUOR 594 Conjugated

Antigen Source

KLH conjugated synthetic peptide derived from human Endothelin-1

Alternative name 1

Endothelin-1(2C4) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated

Storage

Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Advisory

Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.

Background information

Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Anti-Endothelin-1(2C4) Monoclonal, ALEXA Fluor 594

Description:

Size: 100 microliters

Catalog no.: GENTObsm-0954M-A594

Price: 489 EUR