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Providers / Bioss Monoclonal Antibodies / Anti-BNP(H1G3) Monoclonal, ALEXA Fluor 594

Description:

Size: 100 microliters

Catalog no.: GENTObsm-4579M-A594

Price: 489 EUR

Get for 489 EUR on Gentaur.com

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Product details

Target Protein/Peptide

BNP

Gene ID

4879

Clone

H1G3

Applications

IF(IHC-P)

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Modification

Not modified

Conjugated with

ALEXA FLUOR 594

Conjugated

Alexa conjugate 1

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Cross Reactive species

Human (Homo sapiens)

Host organism

Mouse (Mus musculus)

Clonality

Monoclonal Antibodies

Purification method

Purified by Protein G.

Type

Conjugated Primary Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Specificity

Highly specific antibody against BNP

Properties

For facs or microscopy Alexa 1 conjugate.

Cross Reactive Species details

No significant cross reactivity is observed

Alternative name 2

BNP(H1G3) Monoclonal anti-, ALEXA FLUOR 594 Conjugated

Antigen Source

KLH conjugated synthetic peptide derived from human BNP

Alternative name 1

BNP(H1G3) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated

Storage

Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Synonyms

BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein.

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Advisory

Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.

Background information

Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.