Description:

Size: 100 microliters

Catalog no.: GENTObsm-1625M-A594

Price: 489 EUR

Product details

Gene ID

354

Target Protein/Peptide

PSA

Clone

Pa3

Applications

IF(IHC-P)

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Modification

Not modified

Conjugated with

ALEXA FLUOR 594

Conjugated

Alexa conjugate 1

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Cross Reactive species

Human (Homo sapiens)

Host organism

Mouse (Mus musculus)

Clonality

Monoclonal Antibodies

Purification method

Purified by Protein G.

Type

Conjugated Primary Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Specificity

Highly specific antibody against PSA

Properties

For facs or microscopy Alexa 1 conjugate.

Cross Reactive Species details

No significant cross reactivity is observed

Antigen Source

Full length native protein purified from human

Alternative name 2

PSA(Pa3) Monoclonal anti-, ALEXA FLUOR 594 Conjugated

Alternative name 1

PSA(Pa3) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated

Storage

Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Synonyms

Prostate specic antigen; Gamma seminoprotein; hK3; Kallikrein 3; Kallikrein related peptidase 3; KLK 3; KLK2A1; KLK3; P 30 antigen; P30 antigen; Prostate Specic Antigen; PSA; Semenogelase; Seminin.

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Advisory

Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.

Background information

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].