1ug per 1ul
COPA/alpha COP I
Alexa conjugate 1
ALEXA FLUOR® 594
Purified by Protein A.
Polyclonals and antibodies
Conjugated Primary Antibody
Alexa Fluor,ALEXA FLUOR® 594
Rabbit (Oryctolagus cuniculus)
Anti-COPA/alpha COP I Polyclonal
COPA/alpha COP I Polyclonal Antibody
For facs or microscopy Alexa 1 conjugate.
No modification has been applied to this antibody
This antibody reacts specifically with COPA/alpha COP I
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
KLH conjugated synthetic peptide derived from human COPA/alpha COP I
Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Alpha coat protein; Alpha COP; Alpha COPI; AlphaCOP; Coatomer protein complex subunit alpha; Coatomer subunit alpha; COP A; COP I alpha; COPA; COPI alpha; FLJ26320; HEP COP; HEPCOP; Proxenin; Xenin; Xenopsin-related peptide; COPA_HUMAN.
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
The Anti-COPA/alpha COP I is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
COPA (alpha-coat protein) is processed to produce Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and large intestinal motility, and inhibits pentagastrin-stimulated secretion of acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, respectively).