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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / DNA Ligase IV/LIG4 Antibody, ALEXA FLUOR 647

Description:

Size: 100ul

Catalog no.: bs-1677R-A647

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Gene ID Number

3981

Modification Site

None

Swiss Prot

P49917

Subcellular location

Nucleus

French translation

anticorps

Tested applications

IF(IHC-P)

Immunogen range

60-110/911

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 647

Target Antigen

DNA Ligase IV/LIG4

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-DNA Ligase IV/LIG4 PAb ALEXA FLUOR 647

Specificity

This is a highly specific antibody against DNA Ligase IV/LIG4.

Long name

DNA Ligase IV/LIG4 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Synonyms

LIG4S; DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4; LIG4

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNA Ligase IV

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-DNA Ligase IV/LIG4 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.