Description:

Size: 100ul

Catalog no.: bs-4191R-A488

Price: 380 EUR

Product details

Gene ID Number

9507

Modification Site

None

Swiss Prot

O75173

Target Antigen

ADAMTS4

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

499nm/519nm

Immunogen range

530-580/839

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Subcellular location

Extracellular, Secreted

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-ADAMTS4 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against ADAMTS4.

Long name

ADAMTS4 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS4

Synonyms

ADMP-1; ADAMTS-2; ADAMTS-4; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; Aggrecanase-1; ADAMTS4; KIAA0688; UNQ769/PRO1563

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-ADAMTS4 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.