1ug per 1ul
ALEXA FLUOR® 488
Human, Mouse, Rat
Purified by Protein A.
Conjugated Primary Antibodies
Anti-TLX2 PAb ALEXA FLUOR 488
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against TLX2.
TLX2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLX2
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Enx; homeo box 11 like 1; Homeobox protein Hox 11L1; Homeobox TLX 2; HOX11L1; NCX; Neural crest homeobox protein; PMUR10F; T cell leukemia homeobox protein 2; T cell leukemia, homeobox 2.
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-TLX2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
T-cell leukemia homeobox protein 2 (TLX2), also known as homeobox protein Hox-11L1 (HOX11L1), neural crest homeobox protein (NCX) or ENX, is a 284 amino acid member of the TLX homeobox family. The mouse homolog, Tlx2, has been detected in dorsal-root ganglia, cranial and entric-nerve gangla, parasympathetic ganglia and adrenal glands in mouse embryos and in the adrenal glands, intestine and heart of adult mice. The expression pattern of Tlx2, which is restricted to tissues derived from nerual crest cells, suggests that it may play a role in the proliferation or differentiation of the enteric peripheral nervous system. TLX2, which is localized to the nucleus, is highly homologous to mouse Tlx2, and shares several critical domains, including an enhancer element in the promotor that is crucial for tissue-specific expression. Mutations in the gene encoding mouse Tlx2 lead to congenital anomalies closely resembling neuronal intestinal dysplasia in humans. Thus, TLX2 is thought to play a role in this disease, which is a rare condition characterized by hyperplasia of submucosal plexus with giant submucosal ganglia and increased acetylcholinesterase activity in nerve fiber around submucosal blood vessels.