Gene ID Number
3931
LCAT Antibody, ALEXA FLUOR 555
Description:
Size: 100ul
Catalog no.: bs-1972R-A555
Price: 380 EUR
Product details
Modification Site
None
Target Antigen
LCAT
Swiss Prot
P04180
Subcellular location
Secreted
French translation
anticorps
Tested applications
IF(IHC-P)
Clonality
Polyclonal
Modification
Unmodified
Excitation emission
553nm/568nm
Immunogen range
170-220/440
Concentration
1ug per 1ul
Crossreactivity
Human, Mouse, Rat
Conjugated with
ALEXA FLUOR® 555
Clone
Polyclonal antibody
Recommended dilutions
IF(IHC-P)(1:50-200)
Purification
Purified by Protein A.
Conjugation
Alexa Fluor,ALEXA FLUOR 555
Also known as
Anti-LCAT PAb ALEXA FLUOR 555
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Specificity
This is a highly specific antibody against LCAT.
Long name
LCAT Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LCAT
Synonyms
Phosphatidylcholine-sterol acyltransferase; Lecithin-cholesterol acyltransferase; Phospholipid-cholesterol acyltransferase; LCAT
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Properties
For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Background of the antigen
Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.