Gene ID Number
1ug per 1ul
Ser807 + Ser811
Alexa conjugate 1
ALEXA FLUOR® 594
Human, Mouse, Rat
Purified by Protein A.
Rb/P105 RB Ser807 + Ser811
Conjugated Primary Antibodies
Alexa Fluor,ALEXA FLUOR® 594
Rabbit (Oryctolagus cuniculus)
Anti-Rb/P105 RB Ser807 + Ser811 PAb ALEXA FLUOR 594
Rb/P105 RB (Ser807 + Ser811) Antibody, ALEXA FLUOR 594 Conjugated
This is a highly specific antibody against Rb/P105 RB Ser807 + Ser811.
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
KLH conjugated synthetic phosphopeptide derived from human P105 RB around the phosphorylation site of Ser807/Ser811
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
RbSer807; OSRC; P105 RB; P105RB; PP105; PP110; pRb; RB 1; RB1; RB1 protein; Retinoblastoma 1 including osteosarcoma; Retinoblastoma 1; Retinoblastoma associated protein; Retinoblastoma related osteosarcoma; Retinoblastoma susceptibility gene; Including osteosarcoma; RB_HUMAN.
Nuclear MarkerRb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.