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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Adenomatous Polyposis Coli Antibody, ALEXA FLUOR 555

Description:

Size: 100ul

Catalog no.: bs-3680R-A555

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Gene ID Number

324

Modification Site

None

Swiss Prot

P25054

Subcellular location

Cytoplasm

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Excitation emission

553nm/568nm

Concentration

1ug per 1ul

Immunogen range

2790-2843/2843

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 555

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Target Antigen

APC/Adenomatous Polyposis Coli

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-APC/Adenomatous Polyposis Coli PAb ALEXA FLUOR 555

Long name

Adenomatous Polyposis Coli Antibody, ALEXA FLUOR 555 Conjugated

Specificity

This is a highly specific antibody against APC/Adenomatous Polyposis Coli.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

GS; DP2; DP3; BTPS2; DP2.5; PPP1R46; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.