Gene ID Number
1ug per 1ul
Human, Mouse, Rat
ALEXA FLUOR® 555
Purified by Protein A.
Alexa Fluor,ALEXA FLUOR 555
Conjugated Primary Antibodies
APC/Adenomatous Polyposis Coli
Rabbit (Oryctolagus cuniculus)
Anti-APC/Adenomatous Polyposis Coli PAb ALEXA FLUOR 555
Adenomatous Polyposis Coli Antibody, ALEXA FLUOR 555 Conjugated
This is a highly specific antibody against APC/Adenomatous Polyposis Coli.
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
GS; DP2; DP3; BTPS2; DP2.5; PPP1R46; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.