Gene ID Number
6774
STAT3 (Ser727) Antibody, ALEXA FLUOR 647
Description:
Size: 100ul
Catalog no.: bs-3429R-A647
Price: 350 EUR
Product details
Swiss Prot
P40763
Modification Site
Ser727
French translation
anticorps
Tested applications
IF(IHC-P)
Clonality
Polyclonal
Concentration
1ug per 1ul
Immunogen range
710-740/770
Excitation emission
650nm/665nm
Target Antigen
STAT3 Ser727
Modification
Phosphorylation
Conjugated with
ALEXA FLUOR® 647
Crossreactivity
Human, Mouse, Rat
Subcellular location
Cytoplasm, Nucleus
Clone
Polyclonal antibody
Recommended dilutions
IF(IHC-P)(1:50-200)
Purification
Purified by Protein A.
Conjugation
Alexa Fluor,ALEXA FLUOR 647
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Also known as
Anti-STAT3 Ser727 PAb ALEXA FLUOR 647
Specificity
This is a highly specific antibody against STAT3 Ser727.
Long name
STAT3 (Ser727) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Synonyms
APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3
Source
KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Background of the antigen
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Properties
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-STAT3 Ser727 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.