Gene ID Number
1796
DOK1 (Tyr398) Antibody, ALEXA FLUOR 488
Description:
Size: 100ul
Catalog no.: bs-5290R-A488
Price: 350 EUR
Product details
Modification Site
Tyr398
Tested applications
IF(IHC-P)
French translation
anticorps
Clonality
Polyclonal
Excitation emission
499nm/519nm
Conjugation
Alexa Fluor
Target Antigen
DOK1 Tyr398
Concentration
1ug per 1ul
Modification
Phosphorylation
Crossreactivity
Human, Mouse, Rat
Conjugated with
ALEXA FLUOR® 488
Recommended dilutions
IF(IHC-P)(1:50-200)
Clone
Polyclonal antibody
Purification
Purified by Protein A.
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Also known as
Anti-DOK1 Tyr398 PAb ALEXA FLUOR 488
Specificity
This is a highly specific antibody against DOK1 Tyr398.
Long name
DOK1 (Tyr398) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Source
KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms
DOK1 phospho Y398; DOK1 phospho Tyr398; p-DOK1 phospho Y398; docking protein 1 downstream of tyrosine kinase 1; Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62.; docking protein 1 62kD downstream of tyrosine kinase 1; Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62dok; P62DOK; pp62; pp62.
Background of the antigen
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
Properties
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-DOK1 Tyr398 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.