Modification Site
None
RNF158 Antibody, ALEXA FLUOR 555
Description:
Size: 100ul
Catalog no.: bs-9230R-A555
Price: 380 EUR
Product details
Gene ID Number
153769
Target Antigen
RNF158
Tested applications
IF(IHC-P)
French translation
anticorps
Clonality
Polyclonal
Modification
Unmodified
Concentration
1ug per 1ul
Excitation emission
553nm/568nm
Conjugated with
ALEXA FLUOR® 555
Crossreactivity
Human, Mouse, Rat
Clone
Polyclonal antibody
Recommended dilutions
IF(IHC-P)(1:50-200)
Purification
Purified by Protein A.
Conjugation
Alexa Fluor,ALEXA FLUOR 555
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Also known as
Anti-RNF158 PAb ALEXA FLUOR 555
Specificity
This is a highly specific antibody against RNF158.
Long name
RNF158 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF158
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Properties
For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Synonyms
Heart protein phosphatase 1-binding protein; HEPP1; Putative E3 ubiquitin protein ligase SH3RF2; Putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; SH3 domain containing RING finger protein 2; SH3 domain-containing RING finger protein 2; SH3R2_HUMAN; Sh3rf2.
Background of the antigen
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.