Modification Site
None
None
153769
RNF158
IF(IHC-P)
anticorps
Polyclonal
Unmodified
1ug per 1ul
553nm/568nm
ALEXA FLUOR® 555
Human, Mouse, Rat
Polyclonal antibody
IF(IHC-P)(1:50-200)
Purified by Protein A.
Alexa Fluor,ALEXA FLUOR 555
Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
Anti-RNF158 PAb ALEXA FLUOR 555
This is a highly specific antibody against RNF158.
RNF158 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF158
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Heart protein phosphatase 1-binding protein; HEPP1; Putative E3 ubiquitin protein ligase SH3RF2; Putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; SH3 domain containing RING finger protein 2; SH3 domain-containing RING finger protein 2; SH3R2_HUMAN; Sh3rf2.
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.