Gene ID Number
1ug per 1ul
ALEXA FLUOR® 594
Human, Mouse, Rat
Alexa conjugate 1
Nucleus, Cell membrane
Purified by Protein A.
Conjugated Primary Antibodies
Alexa Fluor,ALEXA FLUOR® 594
Rabbit (Oryctolagus cuniculus)
Anti-AKT1/2/3 Tyr474 PAb ALEXA FLUOR 594
This is a highly specific antibody against AKT1/2/3 Tyr474.
AKT1/2/3 (Tyr474) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
KLH conjugated synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Tyr474
RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT1; RAC
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.