Description:

Size: 100ul

Catalog no.: bs-0558R-A647

Price: 380 EUR

Product details

Modification Site

None

Target Antigen

EMP1

Gene ID Number

13730

Swiss Prot

P47801

French translation

anticorps

Tested applications

IF(IHC-P)

Crossreactivity

Mouse, Rat

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

650nm/665nm

Immunogen range

105-135/160

Concentration

1ug per 1ul

Subcellular location

Cell membrane

Conjugated with

ALEXA FLUOR® 647

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Also known as

Anti-EMP1 PAb ALEXA FLUOR 647

Host Organism

Rabbit (Oryctolagus cuniculus)

Specificity

This is a highly specific antibody against EMP1.

Long name

EMP1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Source

KLH conjugated synthetic peptide derived from mouse Emp1

Synonyms

TMP; I-8-9; Epithelial membrane protein 1; EMP-1; Tumor-associated membrane protein; Emp1

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-EMP1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.