Description:

Size: 100ul

Catalog no.: bs-4298R-A488

Price: 380 EUR

Product details

Gene ID Number

972

Modification Site

None

Swiss Prot

P04233

French translation

anticorps

Tested applications

IF(IHC-P)

Modification

Unmodified

Clonality

Polyclonal

Excitation emission

499nm/519nm

Conjugation

Alexa Fluor

Immunogen range

249-290/296

Concentration

1ug per 1ul

Subcellular location

Extracellular

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

HLA class II histocompatibility antigen gamma chain

Long name

CD74 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Also known as

Anti-HLA class II histocompatibility antigen gamma chain PAb ALEXA FLUOR 488

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Specificity

This is a highly specific antibody against HLA class II histocompatibility antigen gamma chain.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HLA class II histocompatibility antigen gamma chain

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

II; DHLAG; HLADG; Ia-GAMMA; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; p33; CD74

Background of the antigen

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-HLA class II histocompatibility antigen gamma chain has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.