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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Amyloid Precursor Protein (T743) Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-3028R-A488

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

351

Modification Site

Thr743

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Excitation emission

499nm/519nm

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Subcellular location

Extracellular

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

Amyloid Precursor Protein Thr743

Also known as

Anti-Amyloid Precursor Protein Thr743 PAb ALEXA FLUOR 488

Long name

Amyloid Precursor Protein (T743) Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against Amyloid Precursor Protein Thr743.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human APP around the phosphorylation site of Thr743

Synonyms

Amyloid Precursor Protein phospho Thr743; Amyloid Precursor Protein phospho Thr743; p-Amyloid Precursor Protein phospho Thr743; APP Thr743;

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Description

Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Amyloid Precursor Protein Thr743 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].