Description:

Size: 100ul

Catalog no.: bs-3907R-A594

Price: 380 EUR

Product details

Gene ID Number

5641

Modification Site

None

Swiss Prot

Q99538

Target Antigen

Legumain

Subcellular location

Lysosome

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Immunogen range

225-275/433

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Crossreactivity

Human, Mouse, Rat

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Legumain PAb ALEXA FLUOR 594

Specificity

This is a highly specific antibody against Legumain.

Long name

Legumain Polyclonal Antibody, ALEXA FLUOR 594 Conjugated

Synonyms

AEP; LGMN1; PRSC1; Legumain; Asparaginyl endopeptidase; Protease, cysteine 1; LGMN

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Legumain

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.