Description:

Size: 100ul

Catalog no.: bs-3152R-A488

Price: 350 EUR

Product details

Gene ID Number

2353

Modification Site

Ser32

Swiss Prot

P01100

French translation

anticorps

Immunogen range

10-60/380

Clonality

Polyclonal

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Excitation emission

499nm/519nm

Target Antigen

c-Fos Ser32

Subcellular location

Intracellular

Tested applications

FCM, IF(IHC-P)

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Also known as

Anti-c-Fos Ser32 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against c-Fos Ser32.

Long name

c-Fos (Ser32) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Ser32

Synonyms

p55; AP-1; C-FOS; Proto-oncogene c-Fos; Cellular oncogene fos; G0/G1 switch regulatory protein 7; FOS; G0S7

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-c-Fos Ser32 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.