Background of the antigen
BCL7B shows high homology to the BCL7A protein, which is known to be directly involved in a complex chromosomal translocation in Burkitt lymphoma cell lines. The specific function of BCL7B has not yet been determined. However, it may play a role in lung tumor development or progression. The BCL7B gene is located at a chromosomal region commonly deleted in the congenital disorder, Williams syndrome.