Description:

Size: 100ul

Catalog no.: bs-3174R-A647

Price: 350 EUR

Product details

Gene ID Number

8841

Modification Site

Ser424

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Crossreactivity

Human, Rat

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Target Antigen

HDAC3 Ser424

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 647

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-HDAC3 Ser424 PAb ALEXA FLUOR 647

Specificity

This is a highly specific antibody against HDAC3 Ser424.

Long name

HDAC3 (Ser424) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human HDAC3 around the phosphorylation site of Ser424

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

HDAC3 phospho S424; HDAC3 phospho Ser424; p-HDAC3 Ser424; RPD3 2; RPD3-2; HD 3; HD3; HDAC 3; Histone deacetylase 3 HD3 RPD3-2; histone deacetylase 3; RPD 3; RPD3; SMAP 45; SMAP-45; SMAP45; HDAC3_HUMAN.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-HDAC3 Ser424 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008].