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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / DMO/Dmrt1a Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-11276R-A488

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Gene ID Number

1761

Modification Site

None

Swiss Prot

Q9Y5R6

Subcellular location

Nucleus

French translation

anticorps

Tested applications

IF(IHC-P)

Immunogen range

50-100/373

Clonality

Polyclonal

Modification

Unmodified

Target Antigen

DMO/Dmrt1a

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-DMO/Dmrt1a PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against DMO/Dmrt1a.

Long name

DMO/Dmrt1a Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

DMT1; CT154; Doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis protein 1; DMRT1

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dmrt1a

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-DMO/Dmrt1a has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).