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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / HSP75/TRAP1 Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-1446R-A488

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Modification Site

None

Gene ID Number

10131

Swiss Prot

Q12931

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Modification

Unmodified

Target Antigen

HSP75/TRAP1

Excitation emission

499nm/519nm

Immunogen range

530-580/704

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Subcellular location

Mitochondrion

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-HSP75/TRAP1 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against HSP75/TRAP1.

Long name

HSP75/TRAP1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSP75

Synonyms

HSP75; HSP 75; HSP90L; TRAP-1; Heat shock protein 75 kDa, mitochondrial; TNFR-associated protein 1; Tumor necrosis factor type 1 receptor-associated protein; TRAP1

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-HSP75/TRAP1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.