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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Integrin beta 3 Antibody, ALEXA FLUOR 647

Description:

Size: 100ul

Catalog no.: bs-0342R-A647

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Gene ID Number

3690

Modification Site

None

Swiss Prot

P05106

French translation

anticorps

Immunogen range

27-77/788

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Crossreactivity

Human, Mouse

Subcellular location

Extracellular

Target Antigen

Integrin beta 3

Conjugated with

ALEXA FLUOR® 647

Tested applications

IF(IHC-P), IF(ICC)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Also known as

Anti-Integrin beta 3 PAb ALEXA FLUOR 647

Specificity

This is a highly specific antibody against Integrin beta 3.

Long name

Integrin beta 3 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; Integrin beta-3; Platelet membrane glycoprotein IIIa; ITGB3

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin beta 3

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Integrin beta 3 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.