Description:

Size: 100ul

Catalog no.: bs-2016R-A594

Price: 380 EUR

Product details

Modification Site

None

French translation

anticorps

Immunogen range

1-38/1048

Tested applications

IF(IHC-P)

Modification

Unmodified

Clonality

Polyclonal

Gene ID Number

3685, 3688

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Subcellular location

Extracellular

Conjugated with

ALEXA FLUOR® 594

Crossreactivity

Human, Mouse, Rat

Conjugated

Alexa conjugate 1

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Target Antigen

Integrin Alpha V + Beta 1

Category

Conjugated Primary Antibodies

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Integrin Alpha V + Beta 1 PAb ALEXA FLUOR 594

Long name

Integrin Alpha V + Beta1 Antibody, ALEXA FLUOR 594 Conjugated

Specificity

This is a highly specific antibody against Integrin Alpha V + Beta 1.

Source

Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

The Anti-Integrin Alpha V + Beta 1 is a α- or alpha protein sometimes glycoprotein present in blood.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).