Description:

Size: 100ul

Catalog no.: bs-11458R-A350

Price: 380 EUR

Product details

Modification Site

None

Gene ID Number

25791

Swiss Prot

Q8N5V2

French translation

anticorps

Subcellular location

Cytoplasm

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

343nm/442nm

Immunogen range

450-500/710

Concentration

1ug per 1ul

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 350

Target Antigen

Ephexin-1/EPHEXIN

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Ephexin-1/EPHEXIN PAb ALEXA FLUOR 350

Specificity

This is a highly specific antibody against Ephexin-1/EPHEXIN.

Long name

Ephexin-1/EPHEXIN Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

EPHEXIN; ARHGEF27; Ephexin-1; Eph-interacting exchange protein; Neuronal guanine nucleotide exchange factor; NGEF

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPHEXIN

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).