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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Ki-67 (Proliferation Marker) Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-2130R-A488

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Gene ID Number

4288

Modification Site

None

Swiss Prot

P46013

Subcellular location

Nucleus

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Immunogen range

1250-1300/3256

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Tested applications

IF(IHC-P), IF(ICC)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Target Antigen

Ki-67 proliferation Marker

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Synonyms

KIA; MIB-; MIB-1; PPP1R15; Antigen KI-67; MKI67

Also known as

Anti-Ki-67 proliferation Marker PAb ALEXA FLUOR 488

Long name

Ki-67 (Proliferation Marker) Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against Ki-67 proliferation Marker.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ki67

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Ki-67 proliferation Marker has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.