Description:

Size: 100ul

Catalog no.: bs-2646R-A488

Price: 380 EUR

Product details

Modification Site

None

Gene ID Number

297596

Swiss Prot

Q5BK54

French translation

anticorps

Tissue

lymphocyte

Modification

Unmodified

Clonality

Polyclonal

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Immunogen range

210-260/525

Conjugation

Alexa Fluor

Subcellular location

Extracellular

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Tested applications

FCM, IF(IHC-P), IF(ICC)

Target Antigen

Lymphocyte Activation Gene 3

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Also known as

Anti-Lymphocyte Activation Gene 3 PAb ALEXA FLUOR 488

Synonyms

CD223; Lymphocyte activation gene 3 protein; LAG-3; Lag3

Long name

Lymphocyte Activation Gene 3 Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against Lymphocyte Activation Gene 3.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Description

cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.

Background of the antigen

Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Lymphocyte Activation Gene 3 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.