Description:

Size: 100ul

Catalog no.: bs-5870R-A555

Price: 380 EUR

Product details

Gene ID Number

5653

Modification Site

None

Target Antigen

KLK6

Swiss Prot

Q92876

French translation

anticorps

Tested applications

IF(IHC-P)

Crossreactivity

Human, Rat

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

553nm/568nm

Immunogen range

200-240/244

Concentration

1ug per 1ul

Conjugated with

ALEXA FLUOR® 555

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Also known as

Anti-KLK6 PAb ALEXA FLUOR 555

Host Organism

Rabbit (Oryctolagus cuniculus)

Subcellular location

Cytoplasm, Nucleus, Secreted, Mitochondrion

Specificity

This is a highly specific antibody against KLK6.

Long name

KLK6 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLK6

Synonyms

hK6; Bssp; Klk7; SP59; PRSS9; PRSS18; Kallikrein-6; Neurosin; Protease M; Serine protease 18; Serine protease 9; Zyme; KLK6

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.