Description:

Size: 100ul

Catalog no.: bs-3140R-A555

Price: 350 EUR

Product details

Gene ID Number

2309

Swiss Prot

O43524

Modification Site

Ser253

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Concentration

1ug per 1ul

Immunogen range

240-280/673

Excitation emission

553nm/568nm

Target Antigen

FoxO3a Ser253

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 555

Crossreactivity

Human, Mouse, Rat

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-FoxO3a Ser253 PAb ALEXA FLUOR 555

Specificity

This is a highly specific antibody against FoxO3a Ser253.

Long name

FoxO3a (Ser253) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253

Synonyms

FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.