Description:

Size: 100ul

Catalog no.: bs-2633R-A350

Price: 380 EUR

Product details

Modification Site

None

Gene ID Number

77125

Target Antigen

IL-33

Swiss Prot

Q8BVZ5

French translation

anticorps

Tested applications

IF(IHC-P)

Crossreactivity

Mouse, Rat

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

343nm/442nm

Immunogen range

214-264/266

Concentration

1ug per 1ul

Conjugated with

ALEXA FLUOR® 350

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Subcellular location

Cytoplasm, Nucleus, Secreted

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-IL-33 PAb ALEXA FLUOR 350

Specificity

This is a highly specific antibody against IL-33.

Long name

IL-33 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Source

KLH conjugated synthetic peptide derived from mouse IL-33

Synonyms

Il-33; Il1f11; NF-HEV; 9230117N10Rik; Interleukin-33; Il33

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.