Description:

Size: 100ul

Catalog no.: bs-4707R-A555

Price: 350 EUR

Product details

Modification Site

K17

Gene ID Number

121504

Swiss Prot

P62805

Subcellular location

Nucleus

Immunogen range

5-40/103

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

553nm/568nm

Modification

Acetylation

Conjugated with

ALEXA FLUOR® 555

Crossreactivity

Human, Mouse, Rat

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Target Antigen

Acetyl-Histone H4K17

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Synonyms

H4/p; Histone H4; HIST1H4A; H4/A; H4FA

Also known as

Anti-Acetyl-Histone H4K17 PAb ALEXA FLUOR 555

Long name

Acetyl-Histone H4(K17) Antibody, ALEXA FLUOR 555 Conjugated

Specificity

This is a highly specific antibody against Acetyl-Histone H4K17.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl-Histone H4K17 by NATs.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acetyl-Histone H4(K17)

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.