Description:

Size: 100ul

Catalog no.: bs-0127R-A555

Price: 380 EUR

Product details

Gene ID Number

581

Target Antigen

Bax

Modification Site

None

Swiss Prot

Q07812

French translation

anticorps

Clonality

Polyclonal

Immunogen range

60-110/192

Modification

Unmodified

Concentration

1ug per 1ul

Excitation emission

553nm/568nm

Subcellular location

Mitochondrion

Conjugated with

ALEXA FLUOR® 555

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Tested applications

FCM, IF(IHC-P), IF(ICC)

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Also known as

Anti-Bax PAb ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Crossreactivity

Human, Mouse, Rat, Pig, Rabbit

Specificity

This is a highly specific antibody against Bax.

Long name

Bax Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Synonyms

BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Bax

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.