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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / GSDML/Gasdermin like Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-13291R-A488

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Modification Site

None

Gene ID Number

55876

Crossreactivity

Human

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Concentration

1ug per 1ul

Excitation emission

499nm/519nm

Conjugation

Alexa Fluor

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Target Antigen

GSDML/Gasdermin like

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-GSDML/Gasdermin like PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against GSDML/Gasdermin like.

Long name

GSDML/Gasdermin like Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

123; 156; Gasdermin B; Gasdermin like protein; Gasdermin-B; Gasdermin-like protein; GSDMB; GSDMB_HUMAN; GSDML; PP4052; PRO2521.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GSDML/Gasdermin like

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-GSDML/Gasdermin like has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

GSDML is a member of the GSDMDC (gasdermin-domain containing) family of proteins. Members of the GSDMDC family are involved in a wide variety of cellular processes, including cell-cycle control, extracellular matrix production, differentiation and apoptosis, and have been associated with the development and progression of cancer. GSDML is a widely expressed protein found in both cancerous and non-cancerous tissues localizing to the cytoplasm and in secretory vesicles. The gene encoding GSDML is thought to have been generated by a duplication event of the GSDM1 gene which encodes gasdermin. In addition, various isoforms exist for GSDML.