Description:

Size: 100ul

Catalog no.: bs-7126R-A555

Price: 380 EUR

Product details

Gene ID Number

8468

Modification Site

None

Target Antigen

FKBP6

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Concentration

1ug per 1ul

Excitation emission

553nm/568nm

Conjugated with

ALEXA FLUOR® 555

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-FKBP6 PAb ALEXA FLUOR 555

Specificity

This is a highly specific antibody against FKBP6.

Long name

FKBP6 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP6

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonyms

36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; EC 5.2.1.8; FK506 binding protein 6; FK506-binding protein 6; FKBP 36; FKBP-36; FKBP-6; FKBP36; fkbp6; FKBP6_HUMAN; Immunophilin FKBP36; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP6; PPIase; PPIase FKBP6; Rotamase.

Background of the antigen

FKBP6 is a 327 amino acid protein that, like other PPIases, accelerate the folding of proteins. As a component in synaptonemal complexes, FKBP6 is involved in homologous chromosomes pairing and male infertility in mice. There has been some suggestion that FKBP6 may play a role in modifying the susceptibility to idiopathic spermatogenic impairment in humans. Ubiquitously expressed in all tissues, FKBP6 is present at highest levels in testis, liver, kidney, skeletal muscle and heart. The gene encoding FKBP6 maps within a region of human chromosome 7 that has been implicated in Williams-Beuren syndrome, a rare developmental disorder involving abnormalities of the cardiovascular and musculoskeletal systems. Hemizygous deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren syndrome.