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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / BLNK(Tyr96) Antibody, ALEXA FLUOR 647

Description:

Size: 100ul

Catalog no.: bs-3054R-A647

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

29760

Crossreactivity

Human

Modification Site

Tyr96

Swiss Prot

Q8WV28

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Immunogen range

70-120/456

Target Antigen

BLNK Tyr96

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 647

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Subcellular location

Cytoplasm, Cell membrane

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-BLNK Tyr96 PAb ALEXA FLUOR 647

Specificity

This is a highly specific antibody against BLNK Tyr96.

Long name

BLNK(Tyr96) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human BLNK around the phosphorylation site of Tyr96 [DS(p-Y)EP]

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa; BLNK

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-BLNK Tyr96 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.