Description:

Size: 100ul

Catalog no.: bs-1508R-A350

Price: 380 EUR

Product details

Modification Site

None

Gene ID Number

13039

Swiss Prot

P06797

Subcellular location

Lysosome

French translation

anticorps

Immunogen range

80-120/334

Modification

Unmodified

Clonality

Polyclonal

Target Antigen

Cathepsin L

Concentration

1ug per 1ul

Excitation emission

343nm/442nm

Conjugated with

ALEXA FLUOR® 350

Crossreactivity

Human, Mouse, Rat

Tested applications

IF(IHC-P), IF(ICC)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Cathepsin L PAb ALEXA FLUOR 350

Recommended dilutions

IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Specificity

This is a highly specific antibody against Cathepsin L.

Long name

Cathepsin L Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Source

KLH conjugated synthetic peptide derived from mouse capsin L1 proprotein

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Gene

CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.

Synonyms

fs; MEP; nkt; Ctsl1; 1190035F06Rik; Cathepsin L1; Cathepsin L; Major excreted protein; p39 cysteine proteinase; Ctsl

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.