Description:

Size: 100ul

Catalog no.: bs-2201R-A488

Price: 350 EUR

Product details

Gene ID Number

9181

Modification Site

Ser886

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Conjugation

Alexa Fluor

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Target Antigen

GEF H1 Ser886

Modification

Phosphorylation

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-GEF H1 Ser886 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against GEF H1 Ser886.

Long name

GEF H1 (Ser886) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.

Synonyms

GEF H1phospho S886; Arhgef2Ser886; Lbcl1; Lfc; mKIAA0651; AA408978; ARHG2; ARHGEF 2; ARHGEF-2; ARHGEF2; GEF; GEF H1; GEF-H1; GEFH1; LFP40; MGC95068; P40; Prolerating cell nucleolar antigen p40; Protein GEF-H1; rho/rac guanine nucleotide exchange factor GEF 2; rho/rac guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-GEF H1 Ser886 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.