Description:

Size: 100ul

Catalog no.: bs-10662R-A488

Price: 380 EUR

Product details

Tested applications

FCM

Modification Site

None

Gene ID Number

2022

Target Antigen

CD105

Swiss Prot

P17813

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Conjugation

Alexa Fluor

Excitation emission

499nm/519nm

Immunogen range

510-545/658

Concentration

1ug per 1ul

Recommended dilutions

FCM(1:20-100)

Subcellular location

Extracellular

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Also known as

Anti-CD105 PAb ALEXA FLUOR 488

Host Organism

Rabbit (Oryctolagus cuniculus)

Synonyms

END; HHT1; ORW1; Endoglin; CD105; ENG

Specificity

This is a highly specific antibody against CD105.

Long name

CD105 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD105

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-CD105 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.