Description:

Size: 100ul

Catalog no.: bs-5242R-A594

Price: 350 EUR

Product details

Gene ID Number

993

Modification Site

Ser124

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Target Antigen

cdc25A Ser124

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 594

Crossreactivity

Human, Mouse, Rat

Conjugated

Alexa conjugate 1

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-cdc25A Ser124 PAb ALEXA FLUOR 594

Specificity

This is a highly specific antibody against cdc25A Ser124.

Long name

cdc25A (Ser124) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human cdc25A around the phosphorylation site of Ser124 [SH(p-S)DS]

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonyms

Cdc 25a; CDC25A2; Cell division cycle 25 homolog A S. pombe; Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform bv D9Ertd393ev Dual specicity phosphatase CDC25A; EC 3.1.3.48; M phase inducer phosphatase 1; MGC115549; MPIP1_HUMAN.

Background of the antigen

Cyclin dependent kinases are positively regulated by association with cyclins and negatively regulated by binding to inhibitory subunits. The activity of cyclin dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of Wee1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1 S phase and G2 for CDC25B, CDC25C is predominantly expressed in G2.