Description:

Size: 100ul

Catalog no.: bs-8571R-A594

Price: 380 EUR

Product details

Gene ID Number

3014

Modification Site

None

Swiss Prot

P16104

Subcellular location

Nucleus

Tested applications

IF(IHC-P)

French translation

anticorps

Immunogen range

90-130/143

Clonality

Polyclonal

Crossreactivity

Human, Rat

Modification

Unmodified

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

Histone H2A.X Ubiquityl Lys119

Synonyms

H2AX; H2A.X; H2A/X; Histone H2AX; Histone H2A.X; H2AFX

Also known as

Anti-Histone H2A.X Ubiquityl Lys119 PAb ALEXA FLUOR 594

Long name

Histone H2A.X (Ubiquityl Lys119) Antibody, ALEXA FLUOR 594 Conjugated

Specificity

This is a highly specific antibody against Histone H2A.X Ubiquityl Lys119.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ubiquityl Histone H2A.X (Lys119)

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.