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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / AKT1/2/3 (Ser472/Ser473/Ser474) Antibody, ALEXA FLUOR 555

Description:

Size: 100ul

Catalog no.: bs-0876R-A555

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

24185

Modification Site

Ser473

Swiss Prot

P47196

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Immunogen range

450-480/480

Concentration

1ug per 1ul

Excitation emission

553nm/568nm

Modification

Phosphorylation

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 555

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

AKT1/2/3 (Ser472/Ser473/Ser474)

Also known as

Anti-AKT1/2/3 (Ser472/Ser473/Ser474) PAb ALEXA FLUOR 555

Long name

AKT1/2/3 (Ser472/Ser473/Ser474) Antibody, ALEXA FLUOR 555 Conjugated

Specificity

This is a highly specific antibody against AKT1/2/3 (Ser472/Ser473/Ser474).

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Ser473

Synonyms

Akt; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; RAC-PK-alpha; Akt1

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.