Description:

Size: 100ul

Catalog no.: bs-1283R-A555

Price: 380 EUR

Product details

Gene ID Number

7159

Modification Site

None

Swiss Prot

Q13625

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

553nm/568nm

Concentration

1ug per 1ul

Target Antigen

ASPP2/p53BP2

Immunogen range

1090-1128/1128

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 555

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-ASPP2/p53BP2 PAb ALEXA FLUOR 555

Specificity

This is a highly specific antibody against ASPP2/p53BP2.

Long name

ASPP2/p53BP2 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASPP2

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; Apoptosis-stimulating of p53 protein 2; Bcl2-binding protein; Renal carcinoma antigen NY-REN-51; Tumor suppressor p53-binding protein 2; p53-binding protein 2; TP53BP2

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.