Synonyms
ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form form II. Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine PE-conjugated form, and has the capacity for the binding to autophagosomes.