Description:

Size: 100 microliters

Catalog no.: GENTObs-11001R-A594

Price: 489 EUR

Product details

Subcellular locations

N/A

Swiss Prot

N/A

Modification site

None

Gene ID

149986

Applications

IF(IHC-P)

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Target Protein/Peptide

FAM61B/LSM14B

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Clonality

Polyclonal Antibody

Clone

Polyclonal Antibodies

Purification method

Purified by Protein A.

Group

Polyclonals and antibodies

Type

Conjugated Primary Antibody

Other name

Anti-FAM61B/LSM14B Polyclonal

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Also known as

FAM61B/LSM14B Polyclonal Antibody

Properties

For facs or microscopy Alexa 1 conjugate.

Modification

No modification has been applied to this antibody

Specificity

This antibody reacts specifically with FAM61B/LSM14B

Antigen Source

KLH conjugated synthetic peptide derived from human FAM61B

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Synonyms

Protein FAM61B; Putative uncharacterized protein C20orf40; LSM14 homolog B SCD6, S. cerevisiae; bA11M20.3; C20orf40; Chromosome 20 open reading frame 40; Family with sequence similarity 61 member B; LSM13; LSM14 homolog B; LSM14B SCD6 homolog B S. cerevisiae; MGC61931; Protein LSM14 homolog B; RNA associated protein 55B; LS14B_HUMAN.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Background information

Sm and Sm-like (LSm) proteins form donut-shaped, ubiquitously expressed heptameric complexes that are involved in various steps of RNA metabolism, including RNA-protein interactions and structural changes that are required during ribosomal subunit assembly. LSm14B, also known as C20orf40, FAM61B or LSM13, is a 385 amino acid protein that exists as multiple alternatively spliced isoforms and may play a role in RNA-related events. The gene encoding LSm14B maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.