Product details

Gene ID

N/A

Swiss Prot

N/A

Subcellular locations

N/A

Modification site

None

Target Protein/Peptide

C10orf4

Applications

IF(IHC-P)

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Clonality

Polyclonal Antibody

Clone

Polyclonal Antibodies

Purification method

Purified by Protein A.

Other name

Anti-C10orf4 Polyclonal

Group

Polyclonals and antibodies

Type

Conjugated Primary Antibody

Also known as

C10orf4 Polyclonal Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Properties

For facs or microscopy Alexa 1 conjugate.

Specificity

This antibody reacts specifically with C10orf4

Modification

No modification has been applied to this antibody

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Antigen Source

KLH conjugated synthetic peptide derived from human C10orf4/FRA10AC1

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Synonyms

Chromosome 10 open reading frame 4; F26C11.1 like; FRA10AC1; FRA10AC1 protein; Fragile site 10q23.3; PRO2972; Protein FRA10AC1; Rare folic acid type fragile site FRA10q23.3 candidate gene 1; F10C1_HUMAN.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Background information

C10orf4, also known as FRA10A or FRA10AC1, is a 315 amino acid nuclear protein that is expressed strongly in kidney, liver, heart, brain and skeletal muscle. Defects in the gene encoding C10orf4 are characterized by an expansion of a polymorphic CGG repeat within the 5'-UTR of the gene; an event that is thought to cause folate-sensitive fragile site FRA10A expression. Expression of this mutated FRA10A protein may be associated with tumorigenesis, neurological disorders and mental retardation. C10orf4 is believed to be conserved between species. Five isoforms of C10orf4, all of which differ in their C-termini, are expressed due to alternative splicing events.

Anti-C10orf4 (Polyclonal), ALEXA Fluor 594

Description:

Size: 100 microliters

Catalog no.: GENTObs-9767R-A594

Price: 489 EUR