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    Providers / Bioss Polyclonal Antibodies / Anti-GGT1 (Polyclonal), ALEXA Fluor 594

    Description:

    Size: 100 microliters

    Catalog no.: GENTObs-2976R-A594

    Price: 489 EUR

    Get for 489 EUR on Gentaur.com

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    Product details

    Gene ID

    2678

    Target Protein/Peptide

    GGT1

    Modification site

    None

    Swiss Prot

    P19440

    Excitation emission

    590nm/617nm

    Concentration

    1ug per 1ul

    Subcellular locations

    Extracellular

    Applications

    FCM, IF(IHC-P)

    Conjugated

    Alexa conjugate 1

    Conjugated with

    ALEXA FLUOR® 594

    Clonality

    Polyclonal Antibody

    Other name

    Anti-GGT1 Polyclonal

    Clone

    Polyclonal Antibodies

    Purification method

    Purified by Protein A.

    Also known as

    GGT1 Polyclonal Antibody

    Group

    Polyclonals and antibodies

    Type

    Conjugated Primary Antibody

    Conjugation

    Alexa Fluor,ALEXA FLUOR® 594

    Host organism

    Rabbit (Oryctolagus cuniculus)

    Applications with corresponding dilutions

    FCM(1:20-100), IF(IHC-P)(1:50-200)

    Properties

    For facs or microscopy Alexa 1 conjugate.

    Specificity

    This antibody reacts specifically with GGT1

    Modification

    No modification has been applied to this antibody

    Antigen Source

    KLH conjugated synthetic peptide derived from human GGT1

    Cross reactive species

    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

    Storage

    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

    Synonyms

    GGT; GTG; CD224; GGT 1; D22S672; D22S732; Gamma-glutamyltranspeptidase 1; Gamma-glutamyltransferase 1; Glutathione hydrolase 1; Leukotriene-C4 hydrolase; GGT1

    Description

    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

    About

    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

    Cross Reactive Species details

    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

    Advisory

    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

    Background information

    Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.