Product details

Subcellular locations

N/A

Swiss Prot

N/A

Gene ID

3221

Modification site

None

Target Protein/Peptide

HOXC4

Applications

IF(IHC-P)

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Clonality

Polyclonal Antibody

Clone

Polyclonal Antibodies

Other name

Anti-HOXC4 Polyclonal

Purification method

Purified by Protein A.

Also known as

HOXC4 Polyclonal Antibody

Group

Polyclonals and antibodies

Type

Conjugated Primary Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Properties

For facs or microscopy Alexa 1 conjugate.

Specificity

This antibody reacts specifically with HOXC4

Modification

No modification has been applied to this antibody

Antigen Source

KLH conjugated synthetic peptide derived from human HOXC4

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Synonyms

CP 19; CP19; Homeo box 3E; Homeo box C4; Homeo box protein HoxC4; Homeobox 3E; Homeobox C4; Homeobox protein CP19; Homeobox protein Hox C4; Homeobox protein Hox-3E; Homeobox protein Hox-C4; Homeobox protein HoxC4; Homeobox3E; HomeoboxC4; HOX 3; Hox 3E; HOX C4; HOX3; Hox3E; HOXC 4; Hoxc4; HXC4_HUMAN.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Background information

Homeobox (HOX) genes, which share a highly conserved 183-bp sequence, encode proteins capable of binding to specific DNA sequences and functioning as transcription factors. During embryogenesis, HOX genes play a critical role in the spatial and temporal differentiation of cells. HoxC4, a sequence-specific transcription factor, belongs to the Antp HOX family and localizes to the nucleus. It functions as a part of a developmental regulatory system, providing cells with specific positional identities on the anterior-posterior axis. HoxC4 expression levels increase with differentiation of lymphoid cells, suggesting its role in the molecular regulation of hematopoiesis. HoxC4 is also expressed in differentiated keratinocytes.

Anti-HOXC4 (Polyclonal), ALEXA Fluor 594

Description:

Size: 100 microliters

Catalog no.: GENTObs-12196R-A594

Price: 489 EUR