Description:

    Size: 100 microliters

    Catalog no.: GENTObs-15125R-A594

    Price: 489 EUR

    Product details

    Swiss Prot

    N/A

    Gene ID

    N/A

    Subcellular locations

    N/A

    Modification site

    None

    Target Protein/Peptide

    C21orf37

    Applications

    IF(IHC-P)

    Concentration

    1ug per 1ul

    Excitation emission

    590nm/617nm

    Conjugated with

    ALEXA FLUOR® 594

    Conjugated

    Alexa conjugate 1

    Applications with corresponding dilutions

    IF(IHC-P)(1:50-200)

    Clonality

    Polyclonal Antibody

    Cross reactive species

    Human (Homo sapiens)

    Clone

    Polyclonal Antibodies

    Purification method

    Purified by Protein A.

    Other name

    Anti-C21orf37 Polyclonal

    Group

    Polyclonals and antibodies

    Type

    Conjugated Primary Antibody

    Also known as

    C21orf37 Polyclonal Antibody

    Conjugation

    Alexa Fluor,ALEXA FLUOR® 594

    Host organism

    Rabbit (Oryctolagus cuniculus)

    Properties

    For facs or microscopy Alexa 1 conjugate.

    Specificity

    This antibody reacts specifically with C21orf37

    Modification

    No modification has been applied to this antibody

    Antigen Source

    KLH conjugated synthetic peptide derived from human C21orf37

    Synonyms

    Chromosome 21 open reading frame 37; hCG_1817258; Putative uncharacterized protein C21orf37; CU037_HUMAN.

    Storage

    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

    Description

    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

    About

    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

    Cross Reactive Species details

    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

    Advisory

    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

    Background information

    C22orf37 (chromosome 22 open reading frame 37), also known as FLJ40542, is a 170 amino acid protein encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.