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Providers / Bioss Polyclonal Antibodies / Anti-ZNF350/ZBRK1 (Polyclonal), ALEXA Fluor 594

Description:

Size: 100 microliters

Catalog no.: GENTObs-12213R-A594

Price: 489 EUR

Get for 489 EUR on Gentaur.com

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Product details

Subcellular locations

N/A

Swiss Prot

N/A

Modification site

None

Gene ID

59348

Applications

IF(IHC-P)

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Target Protein/Peptide

ZNF350/ZBRK1

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

Clonality

Polyclonal Antibody

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Cross reactive species

Human (Homo sapiens)

Clone

Polyclonal Antibodies

Purification method

Purified by Protein A.

Group

Polyclonals and antibodies

Type

Conjugated Primary Antibody

Other name

Anti-ZNF350/ZBRK1 Polyclonal

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Also known as

ZNF350/ZBRK1 Polyclonal Antibody

Properties

For facs or microscopy Alexa 1 conjugate.

Modification

No modification has been applied to this antibody

Specificity

This antibody reacts specifically with ZNF350/ZBRK1

Antigen Source

KLH conjugated synthetic peptide derived from human ZNF350/ZBRK1

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Synonyms

KRAB zinc finger protein ZFQR; ZBRK1; ZFQR; Zinc finger and BRCA1 interacting protein with a KRAB domain 1; Zinc finger and BRCA1-interacting protein with a KRAB domain 1; Zinc finger protein 350; Zinc finger protein ZBRK1; ZN350_HUMAN; ZNF350.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Background information

The transcpritional repressor ZBRK1, also designated zinc finger and BRCA1-interacting protein with a KRAB domain 1 or zinc finger protein 350, belongs to the Krüppel C2H2-type zinc-finger protein family of proteins. ZBRK1 localizes mainly to the nucleus and may be associated with the nuclear matrix. It is a widely expressed protein that binds to BRCA1. ZBRK1 plays an important role in transcriptional regulation. Likely targets of gene regulation are DNA damage response genes, which effect the survival and growth control of cells. ZBRK1 contains an N-terminal KRAB domain, a C-terminal BRCA1-binding region and eight central zinc-fingers.